Machaneh Efraim, responsa and novellae on the Rambam, by R. Efraim Navon. Constantinople: Jonah son of Jacob, [1728]. First edition of the book, considered ever since as a classic work for in-depth study in yeshivot.
Important signatures and glosses.

Copy of R. Yisrael Meir Mizrachi, author of Pri HaAretz, with an inscription in his handwriting and with his signature, where he attests to having received the book from the publisher, son of the author. Lengthy gloss in Sephardic script on p. 1a (presumably in his handwriting).

R. Yisrael Meir Mizrachi (ca. 1690 – ca. 1751), leading Jerusalem Torah scholar in the times of the Or HaChaim. He was raised by his illustrious brother, R. Nissim Chaim Moshe Mizrachi (the Rishon LeTzion, author of Admat Kodesh). His close disciples include R. Yonah Navon, author of Nechpah BaKesef.

Lengthy scholarly gloss on p. 46a (of second sequence; in Sephardic script), signed by R. Yechiel Yaakov Elyakim (b. ca. 1770), prominent Torah scholar in Jerusalem, Constantinople and Salonika. Close disciple of R. Yom Tov Algazi, and son-in-law of R. David Magar, head of the Beit El yeshiva.
Scholarly gloss in Sephardic script by a third writer on p. 19a of last sequence (from around the time of the printing).
Other ownership inscriptions on the title page.

[3], 22; 106; 48 leaves. 31 cm. Condition varies, good-fair to fair-poor. Stains, wear and tears. Extensive worming to first and final leaves, with significant damage to text. Old binding, with leather spine; significant worming.